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Beating Bowel Cancer Community

Stage 4 bowel cancer


Experiences of FOLFOXIRI plus Avastin?

My husband was diagnosed Stage 4 in January, age 39. He has started FOLFIRI, but his KRAS results just came in showing wild type BRAF. His oncologist recommends continuing FOLFIRI plus panitumumab... We went for a second opinion at the Royal Marsden and they recommended FOLFOXIRI plus Avastin (and said they would not give panitumumab due to questions over whether it works in BRAF patients). My husband wants to go for it but worried about side effects having had a tough time on just FOLFIRI so far. Has anyone had FOLFOXIRI as 1st line treatment? How were the side effects?


Hi @EleanorG I’m BRAF and have had lots of Folfoxiri and now Avastin. Same sort of side effects Folfiri I think ?? Mine was cold effects from oxilaplatin and tiredness but you’ll find things build over cycles. No side effects Avastin. There’s quite a few of us with BRAF. Lots love :x:


Ps Do join Shine young persons Fb group cancer - all types not just bowel. @EleanorG :x::x: