Experiences of FOLFOXIRI plus Avastin?
My husband was diagnosed Stage 4 in January, age 39. He has started FOLFIRI, but his KRAS results just came in showing wild type BRAF. His oncologist recommends continuing FOLFIRI plus panitumumab... We went for a second opinion at the Royal Marsden and they recommended FOLFOXIRI plus Avastin (and said they would not give panitumumab due to questions over whether it works in BRAF patients). My husband wants to go for it but worried about side effects having had a tough time on just FOLFIRI so far. Has anyone had FOLFOXIRI as 1st line treatment? How were the side effects?